The undergraduate course, ‘Microgravity Science’, a core course on the BSc Space Science at RMIT University, ran for the first time in 2022. A class of 36 final year undergraduate students designed and constructed nine payloads for operation in microgravity. The conversion of a scientific experiment from the benchtop of a laboratory into a microgravity payload is technically challenging. Over a 12-week period, students were guided through the process of observing a scientific phenomenon using standard laboratory equipment, then converting this experiment into an autonomous, size and weight-restricted payload which could operate in microgravity. Nine payloads were produced to observe a range of scientific phenomena from the physical and life sciences. Experiments studied phenomena in the fields of magnetism, heat transfer, grain pattern formation, foams, crystal growth and plant growth. A systems engineering approach taught students to develop mechanical, power, thermal and data subsystems for the payloads. The experiments manifested as four 2U payloads, one 1.5U payload and four 1U payloads. All experiments contained standard sensors of an accelerometer and camera, driven by an Arduino microcontroller. Individual experiments contained additional sensors as required such as temperature and humidity sensors, pressure sensors and infra-red cameras. In June 2022, six of the nine payloads successfully passed a Flight Readiness Review and flew on a parabolic flight on board a Marchetti Jet from Essendon Fields airport, Victoria, Australia. We present here details of the flight, results from the experiments, lessons learned from the first year of delivery and the challenges of producing microgravity experiments for operation in microgravity. A particular focus will be made on systems integration and the limits on testing due to time constraints; a step frequently underestimated in many space missions.